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Researchers harness cancer resistance mutations to fight tumours

himalaya Diary News Service by himalaya Diary News Service
December 31, 2025
in Education, Global News
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Researchers harness cancer resistance mutations to fight tumours

Illustration depicting tumour infiltrating lymphocyte (TIL) therapy for cancer treatment. During TIL therapy, T-cells (blue) that recognise tumour cells (red) are obtained from a patient. These cells may be genetically engineered with a transgene and then reintroduced to the patient to treat the tumour cells

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An international team of researchers has discovered a new method to fight cancers that no longer respond to treatment.

The team, led by Israel’s Weizmann Institute of Science, used mutations that make tumours drug-resistant to turn them into a potential therapeutic advantage, Xinhua news agency reported.

One of the biggest challenges in cancer care is when a therapy stops working. In many metastatic cancers, drugs that initially show positive results lose their effectiveness over time as cancer cells mutate and continue to grow.

The new study, published in the journal Cancer Discovery, proposes a novel way to confront cancer resistance by harnessing the very mutations that allow tumours to evade treatment.

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